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Consequently, RMs has been an excellent species to use in medical experimentation in such areas as xenotransplantation, behavioral science, neurology, drug testing, cognitive science, and genetics. Not only that, but these primates do not protect themselves with either Abs or CMI against SIVs, but some unknown immunity that, in our opinion is by molecular immunity based on miRNA [1,6,7,28, 2,3,13,14,39,47,48]. One step forward, two steps back--will there ever be an AIDS vaccine? However, for HIV, although numerous vaccines have been tried, no cases of protection are known to have occurred.
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- Medzhitov R, Littman D.
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- Appl Immunohistochem Mol Morphol.
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- Zwick MB.
- Both of these major trials raised hopes, but ultimately each was disappointing in outcome.